Figure 36-3 Arterial PO2 as a function of FIO2 and shunt fraction (S/T). Assumptions are shown on the upper left of the graph. The presence of a shunt decreases arterial PO2 for a given FIO2 . As S/T increases, supplemental O2 has progressively less effect on arterial PO2 . (Adapted from Benumof JL: Anesthesia for Thoracic Surgery, 2nd ed. Philadelphia, WB Saunders, 1995, and Lawler PGP, Nunn JF: A reassessment of the validity of the iso-shunt graph. Br J Anaesth 56:1325, 1984.)


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